SARCOMA- SYMPTOMS AND CAUSES
SARCOMA - SYMPTOMS AND CAUSES
Sarcoma is a type of cancer that can occur in various locations in your body. Sarcoma is the general term for a broad group of cancers that begin in the bones and in the soft (also called connective) tissues (soft tissue sarcoma). Soft tissue sarcoma forms in the tissues that connect, support and surround other body structures. This includes muscle, fat, blood vessels, nerves, tendons and the lining of your joints. There are more than 70 types of sarcoma. Treatment for sarcoma varies depending on sarcoma type, location and other factors.
Signs and symptoms of sarcoma include: A lump that can be felt through the skin that may or may not be painful, Bone pain, A broken bone that happens unexpectedly, such as with a minor injury or no injury at all, Abdominal pain, Weight loss.
It's not clear what causes most sarcomas. In general, cancer forms when changes (mutations) happen in the DNA within cells. The DNA inside a cell is packaged into a large number of individual genes, each of which contains a set of instructions telling the cell what functions to perform, as well as how to grow and divide. Mutations might tell cells to grow and divide uncontrollably and to continue living when normal cells would die. If this happens, the accumulating abnormal cells can form a tumor. Cells can break away and spread (metastasize) to other parts of the body.
Factors that can increase the risk of sarcoma include: Inherited syndromes, Some syndromes that increase the risk of cancer can be passed from parents to children. Examples of syndromes that increase the risk of sarcoma include familial retinoblastoma and neurofibromatosis type 1. Radiation therapy for cancer, Radiation treatment for cancer increases the risk of developing a sarcoma later. Chronic swelling (lymphedema), Lymphedema is swelling caused by a backup of lymph fluid that occurs when the lymphatic system is blocked or damaged. It increases the risk of a type of sarcoma called angiosarcoma. Exposure to chemicals, Certain chemicals, such as some industrial chemicals and herbicides, can increase the risk of sarcoma that affects the liver. Exposure to viruses, The virus called human herpesvirus 8 can increase the risk of a type of sarcoma called Kaposi's sarcoma in people with weakened immune systems.
Journal of Oncology Translational Research with ISSN number: 2476-2261 is a peer reviewed online open access journal seeking to publish articles that includes a wide range of topics in this field and creates a platform for the authors to make their contribution towards the journal. The journal covers all aspects of modern research on cancer, from the more basic discoveries dealing with both cell and molecular biology of tumour cells, to the most advanced clinical assays of conventional and new drugs including risk assessment, cellular and molecular characterization, prevention, detection, diagnosis and treatment of human cancers with the overall goal of improving the clinical care of oncology patients and creates a platform for the authors to contribute towards the journal.
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