Amiodarone-incited aspiratory poisonousness (AIPT) is perhaps the most genuine unfriendly impacts of amiodarone treatment and can be deadly. Along these lines, watchful observing is encouraged. Gauge chest radiograph and pneumonic capacity tests and follow-up chest films at 3-month spans are upheld. Nonetheless, since irregularities on these two assessments don't generally go before manifestations, patient self-reports of respiratory side effects give off an impression of being the best strategy for early location of AIPT. Nitrofurantoin is an antimicrobial medication utilized for treatment of straightforward urinary plot contaminations (UTIs) and as prophylaxis against repetitive UTIs 1. It is liable for aspiratory antagonistic impacts in a little rate (1%) of patients 2-4. Pneumonic poisonousness might be intense/subacute or constant 2-4. Intense/subacute responses are believed to be because of excessive touchiness response and they are autonomous of the measurement 3. Constant aspiratory responses brought about by nitrofurantoin incorporate diffuse interstitial pneumonitis and pneumonic fibrosis and they are identified with the absolute lifetime measurements. We report one instance of nitrofurantoin-prompted lung illness in an on short-patient term nitrofurantoin for UTI prophylaxis. Gemcitabine is a somewhat new deoxycytidine simple (2′,2′-difluorodeoxycytidine) with primary likenesses to cytosine arabinoside (Ara-C). Movement of gemcitabine is exhibited in the therapy of numerous strong tumors, similar to pancreas, ovarian and nonsmall cell cellular breakdown in the lungs (NSCLC). Despite the fact that gemcitabine is considered as a medication with a decent security profile, instances of gemcitabine-prompted serious pneumonic poisonousness (GISPT) were accounted for concerning Ara-C. We played out a deliberate audit of announced cases on the GISPT. 29 clinical preliminaries particularly intriguing NSCLC patients (21) and 21 announced cases recording 40 patients were examined. The rate of the GISPT shifts from 0 to 5%. The clinical show is a subacute clinical condition and is as often as possible vague. The transcendent radiographic example on chest X-beam are reticulo-nodular interstitial invades. It was hypothesized that the physio-neurotic system of the GISPT was a fiery response of the alveolar hairlike divider cytokine-intervened, which made an unusual porousness of its layer. After the differential conclusion were precluded, the cessation of the medication and the early inception of steroids and diuretics are the most every now and again performed medicines. Under these conditions, the result was ideal in a postponement of few days for the most part for a greater part of patients however 20% of patients passed on. Some danger factors, as a past pneumonic sickness or a past thoracic illumination, for the event of the GISPT were proposed. GISPT is uncommon however at times deadly. Its a need to build mindfulness about it to improved an early and appropriate administration of patients growing such a harmfulness after gemcitabine organization.