Immunoglobulin Treatment in Neuromuscular Medicine

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Journal of Brain Research is a peer reviewed, open access journal considering research on all aspects of Neuroscience, Neurodegenerative diseases, Experimental neurology, Functional neurology, Traumatic Brain injury, surgical neurology, Neurological rehabilitation, Neurotoxicology, Neuropharmacology, Neuronal plasticity and Behaviour, clinical neurology, Brain development and Cell differentiation. The Journal aims to provide a platform for the exchange of scientific information addressing research topics in the field of Brain and Neurological sciences.

Intravenous immunoglobulin (IVIg) is used in the treatment of autoimmune diseases, including immune-mediated central and peripheral nervous system disorders. This article will review the indications, proposed mechanism of actions, and administration of immunoglobulin treatment in various neuropathies, neuromuscular junction disorders, and myopathies. IVIg may have more than one mechanism of action to alter the pathogenesis of underlying neuromuscular disease. IVIg treatment has been used as a first-line treatment in Guillain–Barre syndrome, chronic inflammatory demyelinating polyradiculoneuropathy, multifocal motor neuropathy, and second-line off-label treatment in medically refractory cases of polymyositis, dermatomyositis, and myasthenia gravis. IVIg is a well-tolerated and effective treatment for these neuromuscular diseases. With this review article, we hope to increase clinicians' awareness of the indications and efficiencies of IVIg in a broad spectrum of neuromuscular diseases.

The Journal emphasizes high-level research and education. Original research articles, reviews, short communications, and letters to the editors in the fields of Journal of Brain Research are welcome. Every effort is made to have a speedy and critical peer-review process.

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All the manuscripts published by Journal of Brain Research are available freely online immediately after publication without any subscription charges or registration.

All the manuscripts published by Journal of Brain Research are available freely online immediately after publication without any subscription charges or registration.

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